High-Throughput Screening (HTS)

Accelerate Hit Identification with High-Throughput Screening

WuXi Biology and Testing’s high-throughput screening (HTS) platform combines extensive assay development expertise, automated screening technologies, and diverse compound libraries to support efficient hit identification. Access hundreds of established biochemical and cell-based assays or develop fit-for-purpose assays tailored to your target, mechanism, and screening strategy.

Flexible Assay Technologies for HTS

Select from our broad range of assay readouts, including fluorescence, TR-FRET, luminescence, radiometric assays, qPCR, high-content and multiplexed phenotypic assays, and mass spectrometry. Assay formats can be selected and optimized according to target biology and screening objectives.

Our HTS services include access to our compound libraries, enabling screening strategies tailored to your target and program requirements.

200+

Projects Supported

3 Week

Average Turnaround Time of Primary Screens

600K

Data Points Per Week Throughput

Curated and Customizable Compound Libraries for HTS

Our HTS platform includes a curated diversity library of more than 300,000 small molecules selected to provide broad scaffold coverage and drug-like physicochemical properties. Compounds can be screened as a complete collection, selected through cherry-picking, or combined with focused, commercial, or client-provided libraries according to the target and screening strategy.

Focused libraries can also be designed or customized around specific target classes, mechanisms, or project requirements.

Case Study: Target Protein Degradation Hit Finding

We conducted a high-throughput screening campaign evaluating approximately 300k compounds using a target protein degradation HCS assay. The study demonstrates the application of automated high-content screening to large-scale degrader hit identification while maintaining assay performance across the screening campaign.